CRISPR-Cas12技术因其高精度、多组学编辑能力和在免疫治疗中的独特优势，正推动癌症治疗和基因工程的发展，但需解决递送效率和脱靶效应等挑战。 CRISPR-Cas12技术在免疫治疗中的前沿进展与挑战分析 一、技术革新背景与核心优势 CRISPR-Cas12系统作为第三代基因 ...

细菌与噬菌体之间的军备竞赛已经持续了数十亿年。这场没有硝烟的战争催生了地球上最复杂、最精巧的防御系统。当我们以为自己已经通过Cas9、Cas12a或Cas13窥探到了CRISPR-Cas系统的全貌时，自然界总能以一种令人惊叹的方式提醒我们：我们所知的 ...

Show More Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka, Japan; Graduate School of Engineering Science, Osaka University, Osaka, Japan; Osaka International Cancer ...

The applications of CRISPR gene editing technology are ever-expanding. A quick search of the latest publications mentioning CRISPR reveals uses in plant genome engineering, biosensing, genome ...

In a recent study by the team, they discovered the 3D structure of a protein called TnpB, a probable precursor to the CRISPR-Cas12 enzyme. Their findings appeared in the journal Nature. Previous ...

Gene editing is one of the latest breakthroughs in biology. The widely known CRISPR-Cas gene editing system provided prokaryotes (organisms that lack cell nuclei) an immunity against foreign DNA.

CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics. Researchers have now expanded this extensive toolbox further. Their novel ...

CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics. Researchers at the Helmholtz Institute for RNA-based Infection Research (HIRI ...

With the first medical therapy approved and systems like CRISPR-Cas showing up in complex cells, there’s a lot happening in the genome editing field. By Amber Dance/Knowable Magazine Published Jan 26, ...